enantiomers相关论文
Transport and uptake of clausenamide enantiomers in CYP3A4-transfected Caco-2 cells: an insight into
Ain The present study developed a CYP3A4expressed Caco2 monolayer model at which effects of the effluxmetabolism allianc......
(±)-Praeruptorin A enantiomers exert distinct relaxant effects on isolate aorta rings dependent on e
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Highly Enantioselective Michael Addition Promoted by a New Diterpene-Derived Bifunctional Thiourea C
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Nickel(Ⅱ)-catalyzed enantioselective Friedel-Crafts alkylation of indoles with β-CF3-β-(3-indolyl)ni
The bis(3-indolyl)methanes(BIMs)are very important compounds whichpossess a broad range of biological and pharmacologica......
The enantiomers of linalool and other important components of natural oils or natural extracts including cypress oil, ge......
[Objectives]To establish an ultra performance convergence chromatography(UPC2)method to determine the content of enantio......
The red flour beetle,Tribolium castaneum(Coleoptera: Tenebrionidae),is a cosmopolitan pest of stored agricultural pr......
The metabolism and metabolic interconversion study of NNAL enantiomers in rabbit serum by LC-MSMS me
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific nitrosamine, is believed to be important as......
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Comparison of reversed-phase enantioselective HPLC methods for determining the enantiomeric purity o
A simple analytical high-performance liquid chromatography (HPLC) method was applied for the en-antiomeric excess determ......
Performance comparison of chlorinated chiral stationary phases in supercritical fluid chromatography
The effects of two chlorinated chiral stationary phases, namely, Lux Cellulose-2 and Lux i-Cellulose-5, flow-rate, perce......
Stereoselective HPLC Assay of TJ0711 Enantiomers by Precolumn Derivatization with GITC Using UV Dete
the quantitative determination of TJ0711 enantiomers in rat plasma, and it can be used in pharmacokinetic studies....
Main observation and conclusion Two new pairs of monoterpenoid indole alkaloids(MIAs)enantiomers as well as their new co......
建立HPCE手性分离琥珀酸美托洛尔和酒石酸美托洛尔对映体的方法。采用HPCE-CZE模式,在220 nm波长下,以β-CD为手性试剂,成功分离了......
Single-run reversed-phase HPLC method for determining sertraline content, enantiomeric purity, and r
A direct enantio-, diastereo-, and chemo-selective high-performance liquid chromatographic method was developed for dete......
建立一种手性高效液相色谱法分离与分析萘哌地尔对映异构体.采用AD-H(250 mm×4.6 mm,5 μm)色谱柱,检测波长为283 nm;流动相为正......
目的建立甲磺酸加雷沙星异构体的HPLC检测方法。方法 Chiralpak AD-H色谱柱(250 mm×4.6 mm,5μm),柱温:35℃,检测波长:278 nm,流......
苯乙烯广泛存在于环境中,人体少量吸入,没有毒性反应,而长期暴露于高浓度苯乙烯环境,可能引起呼吸系统等相关疾病。扁桃酸是苯乙烯......
,Field responses of the Asian larch bark beetle, Ips subelongatus, to potential aggregation pheromon
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1 Introduction Chiral recognition of substrates is one of the most characteristic phenomena of biological activity. And ......
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
目的：：建立HPLC法同时测定盐酸鲁拉西酮中4种光学异构体的含量测定方法。方法：手性柱为CHIRALPAK AD-H (250 mm ×4.6 mm,5μm)；以正己......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
High performance liquid chromatographic separation of clausenamide enantiomers with chiral-AGP stati
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
测定了16例老年抑郁症患者口服西酞普兰(Citalopram，CIT)后CIT及其代谢物对映体的稳态波谷血药浓度。结果表明，口服20 mg／d后(n=14)，R-......
目的:采用羧甲基-β-环糊精(CM-β-CD)为手性选择剂,建立测定氧氟沙星中对映体含量的毛细管电泳方法。方法:采用未涂层石英毛细管(......
A pair of novel TbⅢ-based enantiomers, [Tb(dbm)3·Lss] (1) and [Tb(dbm)3·LRR] (2) (where Lss=(+)-4,5-pinene bipyridine......
Stereoselective HPLC Assay of TJ0711 Enantiomers by Precolumn Derivatization with GITC Using UV Dete
the quantitative determination of TJ0711 enantiomers in rat plasma, and it can be used in pharmacokinetic studies....
1IntroductionChiral recognition of substrates is one of the most characteristic phenomena of biological activity. And on......
High performance liquid chromatographic separation of clausenamide enantiomers with chiral-AGP stati
A method of high performance liquid chromatographic separation of clausenamide enantiomers with chiral-AGP(α1-acid glyc......
Single-run reversed-phase HPLC method for determining sertraline content,enantiomeric purity,and rel
A direct enantio-,diastereo-,and chemo-selective high-performance liquid chromatographic method was developed for determ......
【目的】游离氨基酸是茶叶的主要化学成分之一,与茶叶的滋味品质密切相关。大多数氨基酸具有手性中心,因此存在滋味特性及生理活性......
测定了１６例老年抑郁症患者口服西酞普兰（Ｃｉｔａｌｏｐｒａｍ，ＣＩＴ）后ＣＩＴ及其代谢物对映体的稳态波谷血药浓度。结果表明，口服２０ｍｇ／ｄ后（ｎ＝１４），Ｒ－ＣＩＴ的平均稳态浓度分别为（３６．２±１５．０）μｇ／Ｌ和（２７．４......
利用分子对接技术预测了2种蛋白质固定相分别与4对手性化合物的相互作用情况。结果表明,预测结合自由能（ΔG）的大小与对映体（R-（＋）型和S-......
建立血浆中华法林对映体密度的立体选择性高效液相色谱法。血浆标本碱洗，酸化和乙醚提后，与碳苄氧基－Ｌ－脯氨酸进行柱前衍生化为差向体。......
目的：考察酮洛芬（Ketoprofen,KT）对映体在多糖衍生物手性固定相的色谱行为,建立酮洛芬对映体的分离分析方法,并用于血浆样品中酮洛芬......
目的建立新药甲磺酸帕珠沙星( PZLX)对映体手性流动相 HPLC拆分方法.方法通过探讨流动相 pH值、有机改性剂、手性配合剂、反相固定......
手性在自然界中无处不在,手性对映体的理化性质极其相似,但手性对映体特别是手性药物在生理活性等方面却表现出明显的差异,因此,有......
目的：研究氨甲喋呤（MTX）对映体对肺癌A549细胞的生长抑制作用。方法：倒置相差显微镜观察加入MTX对映体后细胞形态变化,应用MTT法检测MT......
目的采用HPCE法拆分八种含氨基手性药物对映异构体.方法缓冲液中添加18-冠-6-四甲酸18-Crown-6-(COOH)4(18C6H 4),并且对18C6H4的......
目的:运用高效液相色谱手性流动相法(HPLC-CMP)来拆分甲磺酸帕珠沙星(pz)对映体.方法:通过正交设计直观分析方法,对影响甲磺酸帕珠......
目的：建立西酞普兰对映异构体的拆分方法。方法：采用α1-酸性糖蛋白（AGP）手性柱固定相,考察了流动相组成、pH值、流速、柱温、有机改性......
建立硝酸芬替康唑对映异构体的手性色谱分析方法。通过考察手性固定相、流动相比例以及柱温等因素对硝酸芬替康唑对映异构体分离度......
目的：研究CPU86017及其旋光异构体对L-甲状腺素致大鼠心肌病异常的calcineurin和 NFκB基因改变,并比较CPU86017及其旋光异构体对它......
手性是生物分子的普遍现象，人们对生物体手性分子的产生、复制、再生这种自发生长的生命天然属性的认识、研究，有助于开辟人工合成手......
综述了基于芯片电泳技术的手性分离进展。分别介绍了这一领域的进样、检测技术,所采用的手性选择剂,芯片制作材料及用于提高分离度......
在纤维素-三-（35,-二甲基苯基氨基甲酸酯）（Chiralcel OD-H）手性柱上对硅氟唑对映体的分离进行了研究。考察了流动相中改性剂的种类和浓......
【目的】挥发性萜类化合物是茶叶香气的重要成分,大多数具有手性结构,存在香气特性完全不同的对映异构体。查明不同茶类中挥发性萜......
